human HERC3 Adenovirus

Name
Ad-h-HERC3

Cat No
ADV-210952

Availability
4-5 weeks

This is an Adenovirus expressing Human HERC3.

ADV-210952

Ad-h-HERC3

Ready-to-use Adenovirus expressing Human HERC3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 (PubMed 15676274)).(supplied by OMIM, Mar 2008)

Gene ID

8916

Gene Name (Vector)

HECT and RLD domain containing E3 ubiquitin protein ligase 3

Gene Symbol

HERC3

HGNC ID

HGNC:4876

ORF Size (aa)

3153

ORF Size (bp)

3153 bp

RefSeq ID

NM_014606

RefSeq Synonyms

NM_014606, NM_001318505, NM_001271602, BC166672, BC038960,

Species

human

UniGene ID

Hs.35804

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.