human IKKg shRNA Adenovirus

Name 
Ad-h-IKKg -shRNA
Cat No 
1843
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human IKKg gene. The shRNA expression is driven by an U6 promoter.

The knockdown of this human gene was validated by western blot in A549 cells.

1843
Ad-h-IKKg -shRNA

Ready-to-use human IKKg shRNA Adenovirus. human IKKg shRNA adenovirus gene knockdown1843

$995.00
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Product Details

Promoter
U6 ()
Reporter
eGFP
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume
200 µL

Gene Reference Data

Alternate Names
AMCBX1; FIP-3; FIP3; Fip3p; IKK-gamma; IKKAP1; IKKG; IMD33; IP; IP1; IP2; IPD2; NEMO; ZC2HC9
Description (Vector)
IKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Gene ID
8517
Gene Name (Vector)
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Gene Symbol
IKBKG
HGNC ID
HGNC:5961
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_003639
RefSeq Synonyms
NM_003639, NM_001321397, NM_001321396, NM_001145255, NM_001099857, NM_001099856, BC050612, BC046922, BC012114, BC000299,
Species
human
UniGene ID
Hs.43505

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.