human HBG2 Adenovirus

Name 
Ad-h-HBG2
Cat No 
ADV-210823
Availability
4-5 weeks

This is an Adenovirus expressing Human HBG2.

ADV-210823
Ad-h-HBG2

Ready-to-use Adenovirus expressing Human HBG2 (hemoglobin subunit gamma 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HBG-T1; TNCY
Description (Vector)
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Gene ID
3048
Gene Name (Vector)
hemoglobin subunit gamma 2
Gene Symbol
HBG2
HGNC ID
HGNC:4832
ORF Size (aa)
444
RefSeq ID
NM_000184
RefSeq Synonyms
NM_000184, BC130459, BC130457, BC029387,
Species
human
UniGene ID
Hs.302145

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.