human GZMH Adenovirus
This is an Adenovirus expressing Human GZMH.
ADV-210719
Ad-h-GZMH
Ready-to-use Adenovirus expressing Human GZMH (granzyme H). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CCP-X; CGL-2; CSP-C; CTLA1; CTSGL2
Description (Vector)
GZMH is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Gene ID
2999
Gene Name (Vector)
granzyme H
Gene Symbol
GZMH
HGNC ID
HGNC:4710
ORF Size (aa)
741
ORF Size (bp)
741 bp
RefSeq ID
NM_033423
RefSeq Synonyms
NM_033423, NM_001270781, NM_001270780, BC027974,
Species
human
UniGene ID
Hs.348264
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.