human FGF2 shRNA Adenovirus
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human FGF2 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by qPCR in A549 cells.
1833
Ad-h-FGF2-shRNA
Ready-to-use human FGF2 shRNA Adenovirus. human FGF2 shRNA adenovirus gene knockdown1833
Gene Reference Data
Alternate Names
BFGF; FGF-2; FGFB; HBGF-2
Description (Vector)
FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Gene ID
2247
Gene Name (Vector)
fibroblast growth factor 2
Gene Symbol
FGF2
HGNC ID
HGNC:3676
ORF Size (aa)
867
ORF Size (bp)
867 bp
RefSeq ID
NM_002006
RefSeq Synonyms
NM_002006, BC166646,
Species
human
UniGene ID
Hs.284244
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.