human GCAT Adenovirus
This is an Adenovirus expressing Human GCAT.
ADV-209729
Ad-h-GCAT
Ready-to-use Adenovirus expressing Human GCAT (glycine C-acetyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
KBL
Description (Vector)
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.
Gene ID
23464
Gene Name (Vector)
glycine C-acetyltransferase
Gene Symbol
GCAT
HGNC ID
HGNC:4188
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_014291
RefSeq Synonyms
NM_014291, NM_001171690, BC014457,
Species
human
UniGene ID
Hs.54609
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.