human GBA Adenovirus

Name 
Ad-h-GBA
Cat No 
ADV-209700
Availability
4-5 weeks

This is an Adenovirus expressing Human GBA.

ADV-209700
Ad-h-GBA

Ready-to-use Adenovirus expressing Human GBA (glucosylceramidase beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GBA1; GCB; GLUC
Description (Vector)
GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Gene ID
2629
Gene Name (Vector)
glucosylceramidase beta
Gene Symbol
GBA
HGNC ID
HGNC:4177
ORF Size (aa)
1611
ORF Size (bp)
1611 bp
RefSeq ID
NM_000157
RefSeq Synonyms
NM_001171812, NM_001171811, NM_001005742, NM_001005741, NM_000157, BC003356,
Species
human
UniGene ID
Hs.282997

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.