human FURIN Adenovirus
This is an Adenovirus expressing Human FURIN.
ADV-209407
Ad-h-FURIN
Ready-to-use Adenovirus expressing Human FURIN (furin, paired basic amino acid cleaving enzyme). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FUR; PACE; PCSK3; SPC1
Description (Vector)
FURIN belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene is thought to play a role in tumor progression. The use of alternate polyadenylation sites has been found for this gene.
Gene ID
5045
Gene Name (Vector)
furin, paired basic amino acid cleaving enzyme
Gene Symbol
FURIN
HGNC ID
HGNC:8568
ORF Size (aa)
2385
ORF Size (bp)
2385 bp
RefSeq ID
NM_002569
RefSeq Synonyms
NM_002569, NM_001289824, NM_001289823, BC012181,
Species
human
UniGene ID
Hs.513153
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.