Caveolin 2 Adenovirus
Caveolae (also known as plasmalemmal vesicles) are 50-100 nm membrane domains that represent a subcompartment of the plasma membrane. Caveolae are most abundant in simple squamous epithelia, such as endothelial cells, fibroblasts, smooth muscle cells and adipocytes, but are believed to exist in most cell types. Three types of caveolins, designated caveolin-1, caveolin-2 and caveolin-3, are the principal components of caveolae. Caveolin-1 is a substrate for v-Src protein tyrosine kinase.
1566
Ad-Caveolin-2
Ready-to-use Caveolin 2 Adenovirus. Ad-Caveolin-2, Caveolin 2, Caveolin-2, CAV, CAV2 adenovirus 1566
Gene Reference Data
Alternate Names
CAV
Description (Vector)
CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).
Gene ID
858
Gene Name (Vector)
caveolin 2
Gene Symbol
CAV2
HGNC ID
HGNC:1528
ORF Size (aa)
489
ORF Size (bp)
489 bp
RefSeq ID
NM_001233
RefSeq Synonyms
NM_198212, NM_001233, NM_001206748, NM_001206747, BC005256,
Species
human
UniGene ID
Hs.603096
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.