Serine/threonine kinase 11 Adenovirus
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
1563
Ad-STK11
Ready-to-use Serine/threonine kinase 11 Adenovirus. Ad-STK11, Serine/threonine kinase 11, PJS, LKB1, STK11 adenovirus 1563
Gene Reference Data
Alternate Names
hLKB1; LKB1; PJS
Description (Vector)
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Gene ID
6794
Gene Name (Vector)
serine/threonine kinase 11
Gene Symbol
STK11
HGNC ID
HGNC:11389
ORF Size (aa)
1302
ORF Size (bp)
1302 bp
RefSeq ID
NM_000455
RefSeq Synonyms
NM_000455, BC019334, BC007981,
Species
human
UniGene ID
Hs.515005
Related Citations
- TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway. Su X, etc, (2016), Oncogene
- Loss of LKB1 in Beta Cells Enhances Glucose-Stimulated Insulin Secretion Despite Profound Mitochondrial Defects. A Swisa, etc, (2015), JBC
- LKB1 Destabilizes Microtubules in Myoblasts and Contributes to Myoblast Differentiation. Mian, I. etc, (2012), PLoS ONE
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.