Musculin (activated B-cell factor-1) Adenovirus
Musculin contains a bHLH motif, a putative nuclear localization signal, a glycine-rich region, and a stretch of acidic residues. MSC is capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro, and forms heterodimers with E2A proteins in vivo. MSC contains a transcriptional repression domain and is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. MSC is a downstream target of the B-cell receptor signal transduction pathway.
1555
Ad-Musculin
Ready-to-use Musculin (activated B-cell factor-1) Adenovirus. Ad-Musculin, Musculin (activated B-cell factor-1), Musculin, MSC, ABF1, MYOR, ABF-1 adenovirus 1555
Gene Reference Data
Alternate Names
ABF-1; ABF1; bHLHa22; MYOR
Description (Vector)
MSC is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway.
Gene ID
9242
Gene Name (Vector)
musculin
Gene Symbol
MSC
HGNC ID
HGNC:7321
ORF Size (aa)
621
RefSeq ID
NM_005098
RefSeq Synonyms
NM_005098, BC067827, BC006313,
Species
human
UniGene ID
Hs.442619
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.