human EXOC2 Adenovirus
This is an Adenovirus expressing Human EXOC2.
ADV-208174
Ad-h-EXOC2
Ready-to-use Adenovirus expressing Human EXOC2 (exocyst complex component 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SEC5; SEC5L1; Sec5p
Description (Vector)
EXOC2 is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
Gene ID
55770
Gene Name (Vector)
exocyst complex component 2
Gene Symbol
EXOC2
HGNC ID
HGNC:24968
ORF Size (aa)
2775
ORF Size (bp)
2775 bp
RefSeq ID
NM_018303
RefSeq Synonyms
NM_018303, BC080542,
Species
human
UniGene ID
Hs.484412
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.