human DUS2L Adenovirus
This is an Adenovirus expressing Human DUS2L.
ADV-207403
Ad-h-DUS2L
Ready-to-use Adenovirus expressing Human DUS2 (dihydrouridine synthase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dihydrouridine synthase 2; dihydrouridine synthase 2-like, SMM1 homolog; DUS2L; hDUS2; SMM1; SMM1 homolog; tRNA-dihydrouridine synthase 2-like; tRNA-dihydrouridine(20) synthase (NAD(P)(+)); tRNA-dihydrouridine(20) synthase NAD(P)+-like; up-regulated in lung cancer protein 8; URLC8
Description (eCommerce)
DUS2, also known as DUS2L, encodes for tRNA-dihydrouridine(20) synthase [NAD(P)+]-like that catalyzes the synthesis of dihydrouridine. Dihydrouridine is a modified base found in the D-loop of most tRNAs [taken from UniProtKB (Entry: Q9NX74)].
Description (Vector)
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 (PubMed 15994936)).(supplied by OMIM, Mar 2008)
Gene ID
54920
Gene Name (eCommerce)
dihydrouridine synthase 2
Gene Name (Vector)
dihydrouridine synthase 2
Gene Symbol
DUS2
HGNC ID
HGNC:26014
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1482
ORF Size (bp)
1482 bp
Protein Name (eCommerce)
tRNA-dihydrouridine(20) synthase [NAD(P+)]-like
RefSeq ID
NM_017803
RefSeq Synonyms
NM_017803, NM_001271763, NM_001271762, BC006527,
Research Areas
Mitochondrion,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
DUS2, also known as DUS2L, encodes for tRNA-dihydrouridine(20) synthase [NAD(P)+]-like that catalyzes the synthesis of dihydrouridine. Dihydrouridine is a modified base found in the D-loop of most tRNAs [taken from UniProtKB (Entry: Q9NX74)].
UniGene ID
Hs.534460
UniProt ID (eCommerce)
Q9NX74
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.