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human DPH3 Adenovirus

Name 
Ad-h-DPH3
Cat No 
ADV-207277
Availability
4-5 weeks

This is an Adenovirus expressing Human DPH3.

ADV-207277
Ad-h-DPH3

Ready-to-use Adenovirus expressing Human DPH3 (diphthamide biosynthesis 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DELGIP; DELGIP1; DESR1; DPH3A; KTI11; ZCSL2
Description (Vector)
DPH3 encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform.
Gene ID
285381
Gene Name (Vector)
diphthamide biosynthesis 3
Gene Symbol
DPH3
HGNC ID
HGNC:27717
ORF Size (aa)
249
RefSeq ID
NM_206831
RefSeq Synonyms
NM_206831, NM_001047434, BC010181,
Species
human
UniGene ID
Hs.388087

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.