human DIDO1 Adenovirus

Name 
Ad-h-DIDO1
Cat No 
ADV-206991
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human DIDO1.

ADV-206991
Ad-h-DIDO1

Ready-to-use Adenovirus expressing Human DIDO1 (death inducer-obliterator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BYE1; C20orf158; DATF1; DATF-1; death-associated transcription factor 1; death-inducer obliterator 1; DIDO2; DIDO3; DIO1; DIO-1; dJ885L7.8; hDido1
Description (eCommerce)
DATF1 (Death Associated Transcription Factor 1), also known as DIDO1 (Death-Inducer Obliterator 1), is a putative tumor suppressor associated with the induction of myeloid neoplasms. DATF1 (DIDO1) is one of 3 isoforms (DIDO1, 2, and 3) expressed from the DIDO gene and has been found to be involved in apoptosis and the accurate segregation of chromosomes during mitosis.
Description (Vector)
Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.
Gene ID
11083
Gene Name (eCommerce)
death inducer-obliterator 1
Gene Name (Vector)
death inducer-obliterator 1
Gene Symbol
DIDO1
HGNC ID
HGNC:2680
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3570
ORF Size (bp)
3570 bp
Protein Name (eCommerce)
Death-inducer obliterator 1
RefSeq ID
NM_022105
RefSeq Synonyms
NM_080797, NM_080796, NM_033081, NM_022105, NM_001193370, NM_001193369, BC137177, BC004237, BC000770,
Research Areas
Apoptosis,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
DATF1 (Death Associated Transcription Factor 1), also known as DIDO1 (Death-Inducer Obliterator 1), is a putative tumor suppressor associated with the induction of myeloid neoplasms. DATF1 (DIDO1) is one of 3 isoforms (DIDO1, 2, and 3) expressed from the DIDO gene and has been found to be involved in apoptosis and the accurate segregation of chromosomes during mitosis.
UniGene ID
Hs.517172
UniProt ID (eCommerce)
Q9BTC0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.