human DENND1C Adenovirus
This is an Adenovirus expressing Human DENND1C.
ADV-206867
Ad-h-DENND1C
Ready-to-use Adenovirus expressing Human DENND1C (DENN domain containing 1C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FAM31C
Description (Vector)
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 (PubMed 20154091)).(supplied by OMIM, Nov 2010)
Gene ID
79958
Gene Name (Vector)
DENN domain containing 1C
Gene Symbol
DENND1C
HGNC ID
HGNC:26225
ORF Size (aa)
2406
ORF Size (bp)
2406 bp
RefSeq ID
NM_024898
RefSeq Synonyms
NM_024898, NM_001290331, BC033437,
Species
human
UniGene ID
Hs.236449
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.