cAMP responsive element binding protein 3-like 4 Adenovirus

Name 
Ad-CREB3L4
Cat No 
1436
Availability
Immediate
Categories
Adenovirus, Over-Expression

The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, LZIP (also designated CREB3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-4, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A-mediated CREB phosphorylation induces association with a 265 kDa nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator.

1436
Ad-CREB3L4

Ready-to-use cAMP responsive element binding protein 3-like 4 Adenovirus. Ad-CREB3L4, cAMP responsive element binding protein 3-like 4, JAL,HJAL,ATCE1,CREB3,CREB4,AIBZIP,CREB3L4 adenovirus 1436

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
AIBZIP; ATCE1; CREB3; CREB4; hJAL; JAL
Description (Vector)
CREB3L4 encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
148327
Gene Name (Vector)
cAMP responsive element binding protein 3 like 4
Gene Symbol
CREB3L4
HGNC ID
HGNC:18854
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_130898
RefSeq Synonyms
NM_130898, NM_001255981, NM_001255980, NM_001255979, NM_001255978, BC038962,
Species
human
UniGene ID
Hs.372924

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.