human DEFA6 Adenovirus

Name 
Ad-h-DEFA6
Cat No 
ADV-206800
Availability
4-5 weeks

This is an Adenovirus expressing Human SMIM8.

ADV-206800
Ad-h-DEFA6

Ready-to-use Adenovirus expressing Human DEFA6 (defensin alpha 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DEF6; HD-6
Description (Vector)
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.
Gene ID
1671
Gene Name (Vector)
defensin alpha 6
Gene Symbol
DEFA6
HGNC ID
HGNC:2765
ORF Size (aa)
303
RefSeq ID
NM_001926
RefSeq Synonyms
NM_001926, BC093953, BC093951, BC069769, BC069728, BC069710, BC069667,
Species
human
UniGene ID
Hs.711

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.