human DEFA6 Adenovirus

Name
Ad-h-DEFA6

Cat No
ADV-206800

Availability
4-5 weeks

This is an Adenovirus expressing Human DEFA6.

ADV-206800

Ad-h-DEFA6

Ready-to-use Adenovirus expressing Human DEFA6 (defensin alpha 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

DEF6; HD-6

Description (Vector)

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.

Gene ID

1671

Gene Name (Vector)

defensin alpha 6

Gene Symbol

DEFA6

HGNC ID

HGNC:2765

ORF Size (aa)

303

RefSeq ID

NM_001926

RefSeq Synonyms

NM_001926, BC093953, BC093951, BC069769, BC069728, BC069710, BC069667,

Species

human

UniGene ID

Hs.711

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.