Carnitine O-octanoyltransferase Adenovirus
Carnitine octanoyltransferase is a carnitine acyltransferase that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. This provides a crucial step in the transport of medium- and long-chain acyl-CoA out of the mammalian peroxisome to the cytosol and mitochondria.
1434
Ad-CROT
Ready-to-use Carnitine O-octanoyltransferase Adenovirus. Ad-CROT, Carnitine O-octanoyltransferase, COT, CROT adenovirus 1434
Gene Reference Data
Alternate Names
COT
Description (Vector)
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
Gene ID
54677
Gene Name (Vector)
carnitine O-octanoyltransferase
Gene Symbol
CROT
HGNC ID
HGNC:2366
ORF Size (aa)
1839
ORF Size (bp)
1839 bp
RefSeq ID
NM_021151
RefSeq Synonyms
NM_021151, NM_001243745, NM_001143935, BC051874, BC039004,
Species
human
UniGene ID
Hs.125039
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.