Early growth response 2 (Krox-20 homolog, Drosophila) Adenovirus
Several immediate early response genes are transiently activated in serum- or growth factor-stimulated cells. The early growth response genes encode nuclear proteins Egr-1 (NGFI-A), Egr-2 (Krox20), Egr-3 and Egr-4 (NGFI-C), which contain zinc finger DNA-binding domains closely resembling those of the transcription factor Sp1. The Egr proteins function in transcription regulatory activities surrounding cellular growth, differentiation and function. Wilms¬ø tumor nuclear protein (WT) is an anti-oncogene structurally related to the Egr family.
Ready-to-use Early growth response 2 (Krox-20 homolog, Drosophila) Adenovirus. Ad-EGR2, “Early growth response 2 (Krox-20 homolog, Drosophila)”, EGR2,CMT1D,CMT4E,KROX20, EGR-2 adenovirus 1426
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Gene Reference Data
Related Citations
- Epidermal Growth Factor Receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing Early Growth Response Protein (Egr2) expression. Chandra, A. etc, (2013), JBC
- Novel Pro-Survival Functions Of The Kruppel-Like Transcription Factor Egr2 In Promotion Of Macrophage Colony-Stimulating Factor-Mediated Osteoclast Survival Downstream Of The Mek/Erk Pathway. Bradley, E., etc., (2008), J Biol Chem
