human DCLRE1A Adenovirus
This is an Adenovirus expressing Human DCLRE1A.
ADV-206657
Ad-h-DCLRE1A
Ready-to-use Adenovirus expressing Human DCLRE1A (DNA cross-link repair 1A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DNA cross-link repair 1A protein; DNA-crosslink repair gene SNM1; hSNM1; hSNM1A; PSO2; SNM1; SNM1 homolog A; SNM1A
Description (eCommerce)
SNM1A (DNA cross-link repair 1A protein) may be required for DNA interstrand cross-link repair. SNM1A is also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6PJP8].
Description (Vector)
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 (PubMed 10848582)).(supplied by OMIM, Mar 2008)
Gene ID
9937
Gene Name (eCommerce)
DNA cross-link repair 1A
Gene Name (Vector)
DNA cross-link repair 1A
Gene Symbol
DCLRE1A
HGNC ID
HGNC:17660
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3123
ORF Size (bp)
3123 bp
Protein Name (eCommerce)
DNA cross-link repair 1A protein
RefSeq ID
NM_014881
RefSeq Synonyms
NM_014881, NM_001271816, BC062582, BC013124,
Research Areas
Cell Cycle,Cell Division,DNA Damage/Repair
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
SNM1A (DNA cross-link repair 1A protein) may be required for DNA interstrand cross-link repair. SNM1A is also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6PJP8].
UniGene ID
Hs.1560
UniProt ID (eCommerce)
Q6PJP8
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.