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human CYP2C8 Adenovirus

Name 
Ad-h-CYP2C8
Cat No 
ADV-206485
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CYP2C8.

ADV-206485
Ad-h-CYP2C8

Ready-to-use Adenovirus expressing Human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CPC8; CYPIIC8; MP-12/MP-20
Description (Vector)
CYP2C8 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. CYP2C8 is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene ID
1558
Gene Name (Vector)
cytochrome P450 family 2 subfamily C member 8
Gene Symbol
CYP2C8
HGNC ID
HGNC:2622
ORF Size (aa)
1473
ORF Size (bp)
1473 bp
RefSeq ID
NM_000770
RefSeq Synonyms
NM_001198855, NM_001198854, NM_001198853, NM_000770, BC020596,
Species
human
UniGene ID
Hs.709188

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.