human CTR9 Adenovirus

Name 
Ad-h-CTR9
Cat No 
ADV-206257
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CTR9.

ADV-206257
Ad-h-CTR9

Ready-to-use Adenovirus expressing Human CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Ctr9, Paf1/RNA polymerase II complex component, homolog; p150; p150TSP; RNA polymerase-associated protein CTR9 homolog; SH2 domain binding protein 1 (tetratricopeptide repeat containing); SH2 domain-binding protein 1; SH2BP1; TPR-containing, SH2-binding phosphoprotein; TSBP
Description (eCommerce)
CTR9 is a component of the PAF (polymerase-associated factor) complex which interacts with histone-modifying enzymes and RNA polymerase II and plays a role in a number of transcription-related processes. Recent studies show that CTR9 can regulate IL-6-responsive gene transcription by influencing histone methylation.
Description (Vector)
CTR9, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and PAF1 (MIM 610506) form the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 (PubMed 15632063)).(supplied by OMIM, Mar 2008)
Gene ID
9646
Gene Name (eCommerce)
CTR9 homolog, Paf1/RNA polymerase II complex component
Gene Name (Vector)
CTR9 homolog, Paf1/RNA polymerase II complex component
Gene Symbol
CTR9
HGNC ID
HGNC:16850
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3522
ORF Size (bp)
3522 bp
Protein Name (eCommerce)
RNA polymerase-associated protein CTR9 homolog
RefSeq ID
NM_014633
RefSeq Synonyms
NM_014633, NM_001346279, BC058914,
Research Areas
Cancer,Histone Modification,Interleukin Signaling,JAK-STAT Signaling,RNA Processing,Signal Transduction,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
cancer,cell_biology,genetics,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
CTR9 is a component of the PAF (polymerase-associated factor) complex which interacts with histone-modifying enzymes and RNA polymerase II and plays a role in a number of transcription-related processes. Recent studies show that CTR9 can regulate IL-6-responsive gene transcription by influencing histone methylation.
UniGene ID
Hs.173288
UniProt ID (eCommerce)
Q6PD62

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.