human CRH Adenovirus
This is an Adenovirus expressing Human CRH.
ADV-205994
Ad-h-CRH
Ready-to-use Adenovirus expressing Human CRH (corticotropin releasing hormone). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CRF; CRH1
Description (Vector)
Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
Gene ID
1392
Gene Name (Vector)
corticotropin releasing hormone
Gene Symbol
CRH
HGNC ID
HGNC:2355
ORF Size (aa)
591
ORF Size (bp)
591 bp
RefSeq ID
NM_000756
RefSeq Synonyms
NM_000756, BC011031, BC002599,
Species
human
UniGene ID
Hs.75294
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.