human COPS7B Adenovirus

Name 
Ad-h-COPS7B
Cat No 
ADV-205776
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human COPS7B.

ADV-205776
Ad-h-COPS7B

Ready-to-use Adenovirus expressing Human COPS7B (COP9 signalosome subunit 7B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
COP9 constitutive photomorphogenic homolog subunit 7B; COP9 signalosome complex subunit 7b; CSN7B; JAB1-containing signalosome subunit 7b; SGN7b; signalosome subunit 7b
Description (eCommerce)
CSN7b is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. The CSN also possesses kinase activity.
Gene ID
64708
Gene Name (eCommerce)
COP9 signalosome subunit 7B
Gene Name (Vector)
COP9 signalosome subunit 7B
Gene Symbol
COPS7B
HGNC ID
HGNC:16760
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
822
ORF Size (bp)
822 bp
Protein Name (eCommerce)
COP9 signalosome complex subunit 7b
RefSeq ID
NM_022730
RefSeq Synonyms
NM_022730, NM_001308381, NM_001282952, NM_001282951, NM_001282950, NM_001282949, BC091493, BC010739,
Research Areas
Ubiquitination
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
CSN7b is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. The CSN also possesses kinase activity.
UniGene ID
Hs.335061
UniProt ID (eCommerce)
Q9H9Q2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.