human CLDN7 Adenovirus

Name 
Ad-h-CLDN7
Cat No 
ADV-205387
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CLDN7.

ADV-205387
Ad-h-CLDN7

Ready-to-use Adenovirus expressing Human CLDN7 (claudin 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CEPTRL2; claudin-1; claudin-7; CLDN-7; clostridium perfringens enterotoxin receptor-like 2; CPETRL2; epididymis secretory sperm binding protein; Hs.84359
Description (eCommerce)
CLDN7 plays a major role in tight junction-specific obliteration of the intercellular space. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95471].
Description (Vector)
CLDN7 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
Gene ID
1366
Gene Name (eCommerce)
claudin 7
Gene Name (Vector)
claudin 7
Gene Symbol
CLDN7
HGNC ID
HGNC:2049
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
636
ORF Size (bp)
636 bp
Protein Name (eCommerce)
Claudin-7
RefSeq ID
NM_001307
RefSeq Synonyms
NM_001307, NM_001185023, NM_001185022, BC071844, BC001055,
Research Areas
Host-Virus Interactions,Immunology
Research Areas (Faceted)
infectious_disease,immunology
Species
human
Target Sentence
CLDN7 plays a major role in tight junction-specific obliteration of the intercellular space. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95471].
UniGene ID
Hs.513915
UniProt ID (eCommerce)
O95471

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.