human CKMT1A Adenovirus

Name 
Ad-h-CKMT1A
Cat No 
ADV-205320
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CKMT1A.

ADV-205320
Ad-h-CKMT1A

Ready-to-use Adenovirus expressing Human CKMT1A (creatine kinase, mitochondrial 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CKMT1; mia-CK; U-MtCK
Description (Vector)
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
Gene ID
548596
Gene Name (Vector)
creatine kinase, mitochondrial 1A
Gene Symbol
CKMT1A
HGNC ID
HGNC:31736
ORF Size (aa)
1254
ORF Size (bp)
1254 bp
RefSeq ID
NM_001015001
RefSeq Synonyms
NM_001321929, NM_001321928, NM_001321927, NM_001321926, NM_001015001, BC006467, BC001926,
Species
human
UniGene ID
Hs.654988

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.