human CHTF18 Adenovirus

Name 
Ad-h-CHTF18
Cat No 
ADV-205259
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human BRICD5.

ADV-205259
Ad-h-CHTF18

Ready-to-use Adenovirus expressing Human CHTF18 (chromosome transmission fidelity factor 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C16orf41; C321D2.2; C321D2.3; C321D2.3 (novel protein); C321D2.4; C321D2.4 (novel protein); CHL12; chromosome transmission fidelity protein 18 homolog; Ctf18; CTF18, chromosome transmission fidelity factor 18 homolog; hCTF18; homolog of yeast CHL12; RUVBL; some homology with holliday junction DNA helicase RUVB like
Description (eCommerce)
CTF18 (Chromosome Transmission Fidelity protein 18 homolog) is part of the CTF18-RFC (Replication Factor C) complex composed of CTF18, CTF8, DCC1, and four RFC subunits. This complex has been shown to be important for the establishment of sister chromatid cohesion and functions as a proliferating cell nuclear antigen (PCNA) loader for DNA synthesis.
Description (Vector)
CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 (PubMed 12766176); Bermudez et al., 2003 (PubMed 12930902)).(supplied by OMIM, Dec 2009)
Gene ID
63922
Gene Name (eCommerce)
chromosome transmission fidelity factor 18
Gene Name (Vector)
chromosome transmission fidelity factor 18
Gene Symbol
CHTF18
HGNC ID
HGNC:18435
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2928
ORF Size (bp)
2928 bp
Protein Name (eCommerce)
Chromosome transmission fidelity protein 18 homolog
RefSeq ID
NM_022092
RefSeq Synonyms
NM_022092, BC018184, BC006278,
Research Areas
Cancer,Cell Cycle,DNA Replication,Replication
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,transcription_translation,cell_biology,cell_cycle
Species
human
Target Sentence
CTF18 (Chromosome Transmission Fidelity protein 18 homolog) is part of the CTF18-RFC (Replication Factor C) complex composed of CTF18, CTF8, DCC1, and four RFC subunits. This complex has been shown to be important for the establishment of sister chromatid cohesion and functions as a proliferating cell nuclear antigen (PCNA) loader for DNA synthesis.
UniGene ID
Hs.153850
UniProt ID (eCommerce)
Q8WVB6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.