human CFL2 Adenovirus

Name 
Ad-h-CFL2
Cat No 
ADV-205053
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CFL2.

ADV-205053
Ad-h-CFL2

Ready-to-use Adenovirus expressing Human CFL2 (cofilin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NEM7
Description (Vector)
CFL2 encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Gene ID
1073
Gene Name (Vector)
cofilin 2
Gene Symbol
CFL2
HGNC ID
HGNC:1875
ORF Size (aa)
501
ORF Size (bp)
501 bp
RefSeq ID
NM_021914
RefSeq Synonyms
NM_138638, NM_021914, NM_001243645, BC022876, BC022364, BC011444,
Species
human
UniGene ID
Hs.180141

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.