human CFH Adenovirus

Name
Ad-h-CFH

Cat No
ADV-205044

Availability
4-5 weeks

This is an Adenovirus expressing Human CFH.

ADV-205044

Ad-h-CFH

Ready-to-use Adenovirus expressing Human CFH (complement factor H). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS

Description (Vector)

CFH is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene ID

3075

Gene Name (Vector)

complement factor H

Gene Symbol

CFH

HGNC ID

HGNC:4883

ORF Size (aa)

3696

ORF Size (bp)

3696 bp

RefSeq ID

NM_000186

RefSeq Synonyms

NM_001014975, NM_000186, BC142699, BC037285,

Species

human

UniGene ID

Hs.363396

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.