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human CEP170 Adenovirus

Name 
Ad-h-CEP170
Cat No 
ADV-204987
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CEP170.

ADV-204987
Ad-h-CEP170

Ready-to-use Adenovirus expressing Human CEP170 (centrosomal protein 170). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
centrosomal protein 170kDa; centrosomal protein of 170 kDa; Cep170; FAM68A; KAB; KARP-1-binding protein; KARP1-binding protein; KIAA0470; XRCC5 binding protein
Description (eCommerce)
CEP170 (centrosomal protein 170 kDa) was identified as an interaction partner of polo-like kinase 1 (Plk1), a serine/threonine kinase involved in spindle formation and chromosome segregation. CEP170 is a forkhead-associated domain protein that localizes to the centrosomes and functions to maintain microtubule organization.
Description (Vector)
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.
Gene ID
9859
Gene Name (eCommerce)
centrosomal protein 170
Gene Name (Vector)
centrosomal protein 170
Gene Symbol
CEP170
HGNC ID
HGNC:28920
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4383
ORF Size (bp)
4383 bp
Protein Name (eCommerce)
Centrosomal protein of 170 kDa
RefSeq ID
NM_014812
RefSeq Synonyms
NM_014812, NM_001042405, NM_001042404, BC146790, BC140794,
Research Areas
Cell Cycle,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
CEP170 (centrosomal protein 170 kDa) was identified as an interaction partner of polo-like kinase 1 (Plk1), a serine/threonine kinase involved in spindle formation and chromosome segregation. CEP170 is a forkhead-associated domain protein that localizes to the centrosomes and functions to maintain microtubule organization.
UniGene ID
Hs.533635
UniProt ID (eCommerce)
Q5SW79

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.