Akt2 (Myr) Adenovirus
HA-Akt2 is constructed by fusing the HA tag in frame to the N termini of the coding sequence of wild type Akt2. To construct Myr-HA-Akt2, the c-Src myristoylation sequence was fused in frame to the N terminus of the HA-Akt2 (wild-type) coding sequence. Myr-HA-Akt2 is a constitutively active mutant of Akt2, and it is also referred as Akt2(ca).
1023
Ad-CMV-Akt2 (Myr)
Ready-to-use Akt2 (Myr) Adenovirus. Akt2 constitutively active adenovirus 1023
Related Citations
- Hepatocyte nuclear factor 1a suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription. Patitucci C, etc, (2017), JCI
- H19 long noncoding RNA controls the mRNA decay promoting function of KSRP. M Giovarelli, etc, (2014), PNAS
- Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines. Kimberly A. Foster, etc, (2014), Journal of Neuro-Oncology
- Insulin-Like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-Binding Protein LARP6 Expression and Binding to the 5′ Stem-loop of Col1a1 and Col1a2 mRNA. C Blackstock, etc, (2014), JBC
- TRB3 Function in Cardiac Endoplasmic Reticulum Stress. Joan Avery, (2010), Circulation Research
- Akt2-Mediated Phosphorylation Of Pitx2 Controls Ccnd1 Mrna Decay During Muscle Cell Differentiation. R Gherzi, etc, (2009), Cell Death & Differentiation
- Akt2 Overexpression Plays A Critical Role In The Establishment Of Colorectal Cancer Metastasis. Rychahou, PG. etc, (2008), PNAS
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.