human CDC42BPA Adenovirus
This is an Adenovirus expressing Human CDC42BPA.
ADV-204760
Ad-h-CDC42BPA
Ready-to-use Adenovirus expressing Human CDC42BPA (CDC42 binding protein kinase alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDC42 binding protein kinase alpha (DMPK-like); CDC42 binding protein kinase beta; CDC42-binding protein kinase alpha; DMPK-like alpha; MRCK; MRCK alpha; MRCKA; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; myotonic dystrophy protein kinase-like alpha; PK428; serine/threonine-protein kinase MRCK alpha; ser-thr protein kinase PK428; ser-thr protein kinase related to the myotonic dystrophy protein kinase
Description (eCommerce)
MRCKalpha (myotonic dystrophy kinase-related CDC42-binding kinase alpha) is a serine/threonine protein kinase that acts as a downstream effector of CDC42 and promotes actin reorganization.
Description (Vector)
CDC42BPA is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
Gene ID
8476
Gene Name (eCommerce)
CDC42 binding protein kinase alpha
Gene Name (Vector)
CDC42 binding protein kinase alpha
Gene Symbol
CDC42BPA
HGNC ID
HGNC:1737
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4917
ORF Size (bp)
4917 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase MRCK alpha
RefSeq ID
NM_014826
RefSeq Synonyms
NM_014826, NM_003607, BC156892, BC136333,
Research Areas
Cytoskeleton,Kinase/Phosphatase,Signal Transduction,Zinc-finger
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
MRCKalpha (myotonic dystrophy kinase-related CDC42-binding kinase alpha) is a serine/threonine protein kinase that acts as a downstream effector of CDC42 and promotes actin reorganization.
UniGene ID
Hs.35433
UniProt ID (eCommerce)
Q5VT25
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.