human CCT4 Adenovirus

Name 
Ad-h-CCT4
Cat No 
ADV-204559
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CCT4.

ADV-204559
Ad-h-CCT4

Ready-to-use Adenovirus expressing Human CCT4 (chaperonin containing TCP1 subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Cctd; CCT-DELTA; chaperonin containing t-complex polypeptide 1, delta subunit; chaperonin containing TCP1, subunit 4 (delta); SRB; stimulator of TAR RNA-binding; T-complex protein 1 subunit delta; TCP-1-delta
Description (eCommerce)
Chaperonin containing TCP1 subunit 4 (delta) or CCT4 is a molecular chaperone. It assists with the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex, it may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. It is also known to play a role, in vitro, in the folding of actin and tubulin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P50991].
Description (Vector)
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 (PubMed 9819444)).(supplied by OMIM, Mar 2008)
Gene ID
10575
Gene Name (eCommerce)
chaperonin containing TCP1 subunit 4
Gene Name (Vector)
chaperonin containing TCP1 subunit 4
Gene Symbol
CCT4
HGNC ID
HGNC:1617
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1620
ORF Size (bp)
1620 bp
Protein Name (eCommerce)
T-complex protein 1 subunit delta
RefSeq ID
NM_006430
RefSeq Synonyms
NM_006430, NM_001256721, BC106934, BC106933,
Research Areas
Cytoskeleton,Immunology,Metabolism/Metabolic Process,Protein Folding,Translational Control,Transport
Research Areas (Faceted)
cell_biology,immunology,metabolism,transcription_translation
Species
human
Target Sentence
Chaperonin containing TCP1 subunit 4 (delta) or CCT4 is a molecular chaperone. It assists with the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex, it may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. It is also known to play a role, in vitro, in the folding of actin and tubulin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P50991].
UniGene ID
Hs.421509
UniProt ID (eCommerce)
P50991

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.