human C11ORF30 Adenovirus

Name 
Ad-h-C11ORF30
Cat No 
ADV-202462
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ARHGEF10.

ADV-202462
Ad-h-C11ORF30

Ready-to-use Adenovirus expressing Human EMSY (EMSY, BRCA2 interacting transcriptional repressor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BRCA2-interacting transcriptional repressor EMSY; C11orf30; GL002; protein EMSY
Description (eCommerce)
EMSY has been identified as a protein that interacts with BRCA2 and suppresses BRCA2 transactivational activity. EMSY is amplified in some cases of sporadic human breast and ovarian cancer indicating a role in tumorigenesis that is linked to BRCA2 function. EMSY can also associate with HP1beta and BS69 and may be involved in chromatin remodeling.
Gene ID
56946
Gene Name (eCommerce)
EMSY, BRCA2 interacting transcriptional repressor
Gene Name (Vector)
EMSY, BRCA2 interacting transcriptional repressor
Gene Symbol
EMSY
HGNC ID
HGNC:18071
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3696
ORF Size (bp)
3696 bp
Protein Name (eCommerce)
BRCA2-interacting transcriptional repressor EMSY
RefSeq ID
NM_020193
RefSeq Synonyms
NM_020193, NM_001300944, NM_001300943, NM_001300942, BC143376, BC143374, BC143370, BC117265, BC029375,
Research Areas
Cell Biology,Chromatin Remodeling,DNA Damage/Repair,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
EMSY has been identified as a protein that interacts with BRCA2 and suppresses BRCA2 transactivational activity. EMSY is amplified in some cases of sporadic human breast and ovarian cancer indicating a role in tumorigenesis that is linked to BRCA2 function. EMSY can also associate with HP1beta and BS69 and may be involved in chromatin remodeling.
UniGene ID
Hs.352588
UniProt ID (eCommerce)
Q7Z589

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.