human BOP1 Adenovirus

Name 
Ad-h-BOP1
Cat No 
ADV-202234
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human BOP1.

ADV-202234
Ad-h-BOP1

Ready-to-use Adenovirus expressing Human BOP1 (block of proliferation 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Block of proliferation 1 protein; ribosome biogenesis protein BOP1
Description (eCommerce)
BOP1 (block of proliferation 1) is a component of the PeBoW (Pes1, Bop, WDR12) complex that plays a role in the processing of 28S and 5.8S ribosomal RNAs and the formation of the 60S ribosome. BOP1 contains seven WD repeats and was originally identified as a cDNA which inhibited cell proliferation. The deregulation of the BOP1 gene is proposed to contribute to colorectal tumorigenesis.
Gene ID
23246
Gene Name (eCommerce)
block of proliferation 1
Gene Name (Vector)
block of proliferation 1
Gene Symbol
BOP1
HGNC ID
HGNC:15519
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2241
ORF Size (bp)
2241 bp
Protein Name (eCommerce)
Ribosome biogenesis protein BOP1
RefSeq ID
NM_015201
RefSeq Synonyms
NM_015201, BC017674, BC013980, BC013787,
Research Areas
Cell Cycle,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
BOP1 (block of proliferation 1) is a component of the PeBoW (Pes1, Bop, WDR12) complex that plays a role in the processing of 28S and 5.8S ribosomal RNAs and the formation of the 60S ribosome. BOP1 contains seven WD repeats and was originally identified as a cDNA which inhibited cell proliferation. The deregulation of the BOP1 gene is proposed to contribute to colorectal tumorigenesis.
UniGene ID
Hs.645279
UniProt ID (eCommerce)
Q14137

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.