human BCL2L10 Adenovirus
This is an Adenovirus expressing Human BCL2L10.
ADV-202039
Ad-h-BCL2L10
Ready-to-use Adenovirus expressing Human BCL2L10 (BCL2 like 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BCL-B; bcl2-L-10; Boo; Diva
Description (Vector)
BCL2L10 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L10 contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
Gene ID
10017
Gene Name (Vector)
BCL2 like 10
Gene Symbol
BCL2L10
HGNC ID
HGNC:993
ORF Size (aa)
615
ORF Size (bp)
615 bp
RefSeq ID
NM_020396
RefSeq Synonyms
NM_020396, NM_001306168, BC104443, BC104442, BC093828, BC093826,
Species
human
UniGene ID
Hs.283672
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.