human BCAS3 Adenovirus

Name 
Ad-h-BCAS3
Cat No 
ADV-202020
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human AP2A1.

ADV-202020
Ad-h-BCAS3

Ready-to-use Adenovirus expressing Human BCAS3 (BCAS3, microtubule associated cell migration factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 4/3 fusion protein; breast carcinoma-amplified sequence 3; GAOB1; MAAB; metastasis associated antigen of breast cancer; protein Maab1; Rudhira
Description (eCommerce)
Breast cancer amplified sequence 3 (BCAS3) was identified as a gene overexpressed and amplified in breast cancer cell lines. BCAS3 expression has been shown to be regulated by estrogen receptor alpha (ER alpha) and its coregulator PELP1 (proline-, glutamic acid-, and leucine-rich protein 1). BCAS3 has also been demonstrated to act as a coactivator of ER alpha activity in breast cancer cells and associate with the histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor).
Gene ID
54828
Gene Name (eCommerce)
BCAS3, microtubule associated cell migration factor
Gene Name (Vector)
BCAS3, microtubule associated cell migration factor
Gene Symbol
BCAS3
HGNC ID
HGNC:14347
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2787
ORF Size (bp)
2787 bp
Protein Name (eCommerce)
Breast carcinoma-amplified sequence 3
RefSeq ID
NM_017679
RefSeq Synonyms
NM_017679, NM_001330414, NM_001330413, NM_001320470, NM_001099432, BC143387, BC143386, BC117275, BC001250,
Research Areas
Cancer,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer
Species
human
Target Sentence
Breast cancer amplified sequence 3 (BCAS3) was identified as a gene overexpressed and amplified in breast cancer cell lines. BCAS3 expression has been shown to be regulated by estrogen receptor alpha (ER alpha) and its coregulator PELP1 (proline-, glutamic acid-, and leucine-rich protein 1). BCAS3 has also been demonstrated to act as a coactivator of ER alpha activity in breast cancer cells and associate with the histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor).
UniGene ID
Hs.655028
UniProt ID (eCommerce)
Q9H6U6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.