human B4GALT7 Adenovirus

Name 
Ad-h-B4GALT7
Cat No 
ADV-201920
Availability
4-5 weeks

This is an Adenovirus expressing Human ANP32D.

ADV-201920
Ad-h-B4GALT7

Ready-to-use Adenovirus expressing Human B4GALT7 (beta-1,4-galactosyltransferase 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EDSP1; EDSSLA; XGALT1; XGPT1
Description (Vector)
B4GALT7 is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome.
Gene ID
11285
Gene Name (Vector)
beta-1,4-galactosyltransferase 7
Gene Symbol
B4GALT7
HGNC ID
HGNC:930
ORF Size (aa)
984
ORF Size (bp)
984 bp
RefSeq ID
NM_007255
RefSeq Synonyms
NM_007255, BC072403, BC062983, BC007317,
Species
human
UniGene ID
Hs.455109

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.