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human B3GALNT1 Adenovirus

Name 
Ad-h-B3GALNT1
Cat No 
ADV-201870
Availability
4-5 weeks

This is an Adenovirus expressing Human B3GALNT1.

ADV-201870
Ad-h-B3GALNT1

Ready-to-use Adenovirus expressing Human B3GALNT1 (beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B3GALT3; beta3Gal-T3; galT3; Gb4Cer; GLCT3; GLOB; P; P1
Description (Vector)
B3GALNT1 is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein.
Gene ID
8706
Gene Name (Vector)
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
Gene Symbol
B3GALNT1
HGNC ID
HGNC:918
ORF Size (aa)
996
ORF Size (bp)
996 bp
RefSeq ID
NM_003781
RefSeq Synonyms
NM_033169, NM_033168, NM_033167, NM_003781, NM_001038628, BC047618, BC028571,
Species
human
UniGene ID
Hs.418062

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.