human ATP6V1A Adenovirus

Name 
Ad-h-ATP6V1A
Cat No 
ADV-201756
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ANKRD17.

ADV-201756
Ad-h-ATP6V1A

Ready-to-use Adenovirus expressing Human ATP6V1A (ATPase H+ transporting V1 subunit A). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARCL2D; ATP6A1; ATP6V1A1; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; ATPase, H+ transporting, lysosomal, subunit A1; H(+)-transporting two-sector ATPase, subunit A; H+-transporting ATPase chain A, vacuolar (VA68 type); HO68; IECEE3; VA68; vacuolar ATP synthase catalytic subunit A, ubiquitous isoform; vacuolar ATPase isoform VA68; vacuolar proton pump alpha subunit 1; vacuolar proton pump subunit alpha; V-ATPase 69 kDa subunit; V-ATPase 69 kDa subunit 1; V-ATPase A subunit 1; V-ATPase subunit A; Vma1; VPP2; V-type proton ATPase catalytic subunit A
Description (eCommerce)
The gene ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The component, V-type proton ATPase catalytic subunit A, is one of two V1 domain A subunit isoforms and is found in all tissues [taken from NCBI Entrez Gene (Gene ID: 523)].
Description (Vector)
ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist.
Gene ID
523
Gene Name (eCommerce)
ATPase H+ transporting V1 subunit A
Gene Name (Vector)
ATPase H+ transporting V1 subunit A
Gene Symbol
ATP6V1A
HGNC ID
HGNC:851
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1854
ORF Size (bp)
1854 bp
Protein Name (eCommerce)
V-type proton ATPase catalytic subunit A
RefSeq ID
NM_001690
RefSeq Synonyms
NM_001690, BC013138,
Research Areas
Immunology,Insulin Signaling,Mitochondrion,Neurobiology,Signal Transduction
Research Areas (Faceted)
cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
The gene ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The component, V-type proton ATPase catalytic subunit A, is one of two V1 domain A subunit isoforms and is found in all tissues [taken from NCBI Entrez Gene (Gene ID: 523)].
UniGene ID
Hs.477155
UniProt ID (eCommerce)
P38606

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.