human ARHGEF6 Adenovirus

Name 
Ad-h-ARHGEF6
Cat No 
ADV-201372
Availability
4-5 weeks

This is an Adenovirus expressing Human ALDH1B1.

ADV-201372
Ad-h-ARHGEF6

Ready-to-use Adenovirus expressing Human ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
alphaPIX; alpha-PIX; COOL2; Cool-2; MRX46; PAK-interacting exchange factor alpha; PAK-interacting exchange factor, alpha; PIXA; Rac/Cdc42 guanine exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; Rac/Cdc42 guanine nucleotide exchange factor 6; rho guanine nucleotide exchange factor 6
Description (eCommerce)
Rho guanine nucleotide exchange factor 6 (ARHGEF6) functions as a guanine nucleotide exchange factor (GEF) for RAC1. ARHGEF6 was originally identified as a binding partner of p21 activated kinase (Pak) and was termed Pix (Pak interactive exchange factor).
Description (Vector)
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.
Gene ID
9459
Gene Name (eCommerce)
Rac/Cdc42 guanine nucleotide exchange factor 6
Gene Name (Vector)
Rac/Cdc42 guanine nucleotide exchange factor 6
Gene Symbol
ARHGEF6
HGNC ID
HGNC:685
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2331
ORF Size (bp)
2331 bp
Protein Name (eCommerce)
Rho guanine nucleotide exchange factor 6
RefSeq ID
NM_004840
RefSeq Synonyms
NM_004840, NM_001306177, BC043505, BC039856,
Research Areas
Apoptosis,Cancer,Cytoskeleton,GPCR Signaling,Immunology,Neurobiology,Neurodevelopment,NGF Signaling,PDGF Signaling,Rho Signaling,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,immunology,neurobiology,developmental_biology,signal_transduction,immunology
Species
human
Target Sentence
Rho guanine nucleotide exchange factor 6 (ARHGEF6) functions as a guanine nucleotide exchange factor (GEF) for RAC1. ARHGEF6 was originally identified as a binding partner of p21 activated kinase (Pak) and was termed Pix (Pak interactive exchange factor).
UniGene ID
Hs.522795
UniProt ID (eCommerce)
Q15052

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.