human APBA3 Adenovirus

Name 
Ad-h-APBA3
Cat No 
ADV-201119
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human APBA3.

ADV-201119
Ad-h-APBA3

Ready-to-use Adenovirus expressing Human APBA3 (amyloid beta precursor protein binding family A member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
adapter protein X11gamma; amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2); amyloid-beta A4 precursor protein-binding family A member 3; MGC:15815; mint3; mint-3; neuronal munc18-1-interacting protein 3; neuron-specific X11L2 protein; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; X11L2; X11-like 2 protein
Description (eCommerce)
Amyloid beta A4 precursor protein-binding family A member 3 (APBA3) may modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. APBA3 may enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O96018].
Description (Vector)
APBA3 is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.
Gene ID
9546
Gene Name (eCommerce)
amyloid beta precursor protein binding family A member 3
Gene Name (Vector)
amyloid beta precursor protein binding family A member 3
Gene Symbol
APBA3
HGNC ID
HGNC:580
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1728
ORF Size (bp)
1728 bp
Protein Name (eCommerce)
Amyloid beta A4 precursor protein-binding family A member 3
RefSeq ID
NM_004886
RefSeq Synonyms
NM_004886, BC086306, BC008338,
Research Areas
Gene Expression,Neurobiology
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Amyloid beta A4 precursor protein-binding family A member 3 (APBA3) may modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. APBA3 may enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O96018].
UniGene ID
Hs.465607
UniProt ID (eCommerce)
O96018

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.