human APBA1 Adenovirus

Name 
Ad-h-APBA1
Cat No 
ADV-201116
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human APBA1.

ADV-201116
Ad-h-APBA1

Ready-to-use Adenovirus expressing Human APBA1 (amyloid beta precursor protein binding family A member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
adapter protein X11alpha; adaptor protein X11alpha; amyloid beta (A4) precursor protein-binding, family A, member 1 (X11); amyloid-beta A4 precursor protein-binding family A member 1; D9S411E; LIN10; MINT1; mint-1; neuronal munc18-1-interacting protein 1; neuron-specific X11 protein; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; X11; X11A; X11ALPHA
Description (eCommerce)
Amyloid beta A4 precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients [taken from NCBI Entrez Gene (Gene ID: 320)].
Description (Vector)
APBA1 is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Gene ID
320
Gene Name (eCommerce)
amyloid beta precursor protein binding family A member 1
Gene Name (Vector)
amyloid beta precursor protein binding family A member 1
Gene Symbol
APBA1
HGNC ID
HGNC:578
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2514
ORF Size (bp)
2514 bp
Protein Name (eCommerce)
Amyloid beta A4 precursor protein-binding family A member 1
RefSeq ID
NM_001163
RefSeq Synonyms
NM_001163, BC157030, BC156047,
Research Areas
Golgi Apparatus,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
Amyloid beta A4 precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients [taken from NCBI Entrez Gene (Gene ID: 320)].
UniGene ID
Hs.592974
UniProt ID (eCommerce)
Q02410

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.