human ANPEP Adenovirus
This is an Adenovirus expressing Human ANPEP.
ADV-201034
Ad-h-ANPEP
Ready-to-use Adenovirus expressing Human ANPEP (alanyl aminopeptidase, membrane). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APN; CD13; GP150; LAP1; P150; PEPN
Description (Vector)
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Gene ID
290
Gene Name (Vector)
alanyl aminopeptidase, membrane
Gene Symbol
ANPEP
HGNC ID
HGNC:500
ORF Size (aa)
2904
ORF Size (bp)
2904 bp
RefSeq ID
NM_001150
RefSeq Synonyms
NM_001150, BC058928,
Species
human
UniGene ID
Hs.1239
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.