human ALOX5 Adenovirus

Name 
Ad-h-ALOX5
Cat No 
ADV-200802
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ADAT1.

ADV-200802
Ad-h-ALOX5

Ready-to-use Adenovirus expressing Human ALOX5 (arachidonate 5-lipoxygenase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
5-LO; 5-LOX; 5LPG; LOG5
Description (Vector)
ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
240
Gene Name (Vector)
arachidonate 5-lipoxygenase
Gene Symbol
ALOX5
HGNC ID
HGNC:435
ORF Size (aa)
2025
ORF Size (bp)
2025 bp
RefSeq ID
NM_000698
RefSeq Synonyms
NM_001320862, NM_001320861, NM_001256154, NM_001256153, NM_000698, BC143985, BC132677, BC130332,
Species
human
UniGene ID
Hs.89499

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.