human ACACB Adenovirus

Name
Ad-h-ACACB

Cat No
ADV-200147

Availability
4-5 weeks

This is an Adenovirus expressing Human ACACB.

ADV-200147

Ad-h-ACACB

Ready-to-use Adenovirus expressing Human ACACB (acetyl-CoA carboxylase beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ACC2; ACCB; HACC275

Description (Vector)

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

Gene ID

Gene Name (Vector)

acetyl-CoA carboxylase beta

Gene Symbol

ACACB

HGNC ID

HGNC:85

ORF Size (aa)

7377

ORF Size (bp)

7377 bp

RefSeq ID

NM_001093

RefSeq Synonyms

NM_001093, BC172569, BC172264,

Species

human

UniGene ID

Hs.234898

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.