human ABCD4 Adenovirus
This is an Adenovirus expressing Human ABCD4.
ADV-200089
Ad-h-ABCD4
Ready-to-use Adenovirus expressing Human ABCD4 (ATP binding cassette subfamily D member 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
Description (Vector)
ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.
Gene ID
5826
Gene Name (Vector)
ATP binding cassette subfamily D member 4
Gene Symbol
ABCD4
HGNC ID
HGNC:68
ORF Size (aa)
1821
ORF Size (bp)
1821 bp
RefSeq ID
NM_005050
RefSeq Synonyms
NM_005050, BC012815,
Species
human
UniGene ID
Hs.94395
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.