human ABCD3 Adenovirus

Name
Ad-h-ABCD3

Cat No
ADV-200088

Availability
4-5 weeks

This is an Adenovirus expressing Human ABCD3.

ADV-200088

Ad-h-ABCD3

Ready-to-use Adenovirus expressing Human ABCD3 (ATP binding cassette subfamily D member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ABC43; CBAS5; PMP70; PXMP1; ZWS2

Description (Vector)

ABCD3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

5825

Gene Name (Vector)

ATP binding cassette subfamily D member 3

Gene Symbol

ABCD3

HGNC ID

HGNC:67

ORF Size (aa)

1650

ORF Size (bp)

1650 bp

RefSeq ID

NM_002858

RefSeq Synonyms

NM_002858, NM_001122674, BC068509,

Species

human

UniGene ID

Hs.700576

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.