human ABCC1 Adenovirus

Name
Ad-h-ABCC1

Cat No
ADV-200070

Availability
4-5 weeks

This is an Adenovirus expressing Human ABCC1.

ADV-200070

Ad-h-ABCC1

Ready-to-use Adenovirus expressing Human ABCC1 (ATP binding cassette subfamily C member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ABC29; ABCC; ATP-binding cassette sub-family C member 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex25&26; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; GS-X; leukotriene C(4) transporter; LTC4 transporter; MRP; MRP1; multidrug resistance-associated protein 1

Description (eCommerce)

Multidrug resistance-associated protein 1 (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. MRP1 functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. MRP1 also transports glucuronides and sulfate conjugates of steroid hormones and bile salts [taken from NCBI Entrez Gene (Gene ID: 4363)].

Description (Vector)

ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.

Gene ID

4363

Gene Name (eCommerce)

ATP binding cassette subfamily C member 1

Gene Name (Vector)

ATP binding cassette subfamily C member 1

Gene Symbol

ABCC1

HGNC ID

HGNC:51

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4596

ORF Size (bp)

4596 bp

Protein Name (eCommerce)

Multidrug resistance-associated protein 1

RefSeq ID

NM_004996

RefSeq Synonyms

NM_019900, NM_019899, NM_019898, NM_019862, NM_004996, BC157105, BC156353,

Research Areas

Cancer,Golgi Apparatus,Kinase/Phosphatase,Metabolism/Metabolic Process,MicroRNAs in Cancer,Neurobiology,Signal Transduction

Research Areas (Faceted)

cancer,genetics,signal_transduction,cell_biology,metabolism,neurobiology

Species

human

Target Sentence

UniGene ID

Hs.709181

UniProt ID (eCommerce)

P33527

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.